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Aligner-mediated cleavage of nucleic acids and its application to isothermal exponential amplification

We herein describe a simple and versatile approach to use conventional nicking endonuclease (NEase) for programmable sequence-specific cleavage of DNA, termed aligner-mediated cleavage (AMC), and its application to DNA isothermal exponential amplification (AMC-based strand displacement amplification...

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Detalles Bibliográficos
Publicado en:Chem Sci
Main Authors: Wu, Wanghua, Zhang, Tao, Han, Da, Fan, Hongliang, Zhu, Guizhi, Ding, Xiong, Wu, Cuichen, You, Mingxu, Qiu, Liping, Li, Juan, Zhang, Liqin, Lian, Xiang, Hu, Rong, Mu, Ying, Zhou, Jianguang, Tan, Weihong
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916018/
https://ncbi.nlm.nih.gov/pubmed/29732089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc05141g
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