Combined Inhibition of ATR and WEE1 as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer

Triple negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer that poses a clinical challenge. Thus, new therapy strategies are urgently needed. The selective WEE1 inhibitor, AZD1775, has shown strong anti-proliferative effects on a variety of tumors. Here, we first demonstrat...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Jin, Juan, Fang, Hehui, Yang, Fang, Ji, Wenfei, Guan, Nan, Sun, Zijia, Shi, Yaqin, Zhou, Guohua, Guan, Xiaoxiang
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
Assuntos:
Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915994/
https://ncbi.nlm.nih.gov/pubmed/29605721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.03.003
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