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Serotonin receptor and dendritic plasticity in the spinal cord mediated by chronic serotonergic pharmacotherapy combined with exercise following complete SCI in the adult rat

Severe spinal cord injury (SCI) damages descending motor and serotonin (5-HT) fiber projections leading to paralysis and serotonin depletion. 5-HT receptors (5-HTRs) subsequently upregulate following 5-HT fiber degeneration, and dendritic density decreases indicative of atrophy. 5-HT pharmacotherapy...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Ganzer, Patrick D., Beringer, Carl R., Shumsky, Jed S., Nwaobasi, Chiemela, Moxon, Karen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915900/
https://ncbi.nlm.nih.gov/pubmed/29526741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2018.03.006
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