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Serotonin receptor and dendritic plasticity in the spinal cord mediated by chronic serotonergic pharmacotherapy combined with exercise following complete SCI in the adult rat

Severe spinal cord injury (SCI) damages descending motor and serotonin (5-HT) fiber projections leading to paralysis and serotonin depletion. 5-HT receptors (5-HTRs) subsequently upregulate following 5-HT fiber degeneration, and dendritic density decreases indicative of atrophy. 5-HT pharmacotherapy...

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Podrobná bibliografie
Vydáno v:Exp Neurol
Hlavní autoři: Ganzer, Patrick D., Beringer, Carl R., Shumsky, Jed S., Nwaobasi, Chiemela, Moxon, Karen A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915900/
https://ncbi.nlm.nih.gov/pubmed/29526741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2018.03.006
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