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Hypoxia and hypoxia-inducible factors in neuroblastoma

Hypoxia (i.e., low oxygen levels) is a known feature of aggressive tumors. Cells, including tumor cells, respond to conditions of insufficient oxygen by activating a transcriptional program mainly driven by hypoxia-inducible factors (HIF)-1 and HIF-2. Both HIF-1α and HIF-2α expression levels have be...

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Bibliografiske detaljer
Udgivet i:Cell Tissue Res
Main Authors: Påhlman, Sven, Mohlin, Sofie
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915502/
https://ncbi.nlm.nih.gov/pubmed/29032465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-017-2701-1
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