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Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin

Long ncRNAs are often enriched in the nucleus and at chromatin, but whether their dissociation from chromatin is important for their role in transcription regulation is unclear. Here, we group long ncRNAs using epigenetic marks, expression and strength of chromosomal interactions; we find that long...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Ntini, Evgenia, Louloupi, Annita, Liz, Julia, Muino, Jose M., Marsico, Annalisa, Ørom, Ulf Andersson Vang
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915440/
https://ncbi.nlm.nih.gov/pubmed/29691407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04100-3
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