Decreased serum pyridoxal levels in schizophrenia: meta-analysis and Mendelian randomization analysis

BACKGROUND: Alterations in one-carbon metabolism have been associated with schizophrenia, and vitamin B6 is one of the key components in this pathway. METHODS: We first conducted a case–control study of serum pyridoxal levels and schizophrenia in a large Japanese cohort (n = 1276). Subsequently, we...

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Veröffentlicht in:J Psychiatry Neurosci
Hauptverfasser: Tomioka, Yukiko, Numata, Shusuke, Kinoshita, Makoto, Umehara, Hidehiro, Watanabe, Shin-ya, Nakataki, Masahito, Iwayama, Yoshimi, Toyota, Tomoko, Ikeda, Masashi, Yamamori, Hidenaga, Shimodera, Shinji, Tajima, Atsushi, Hashimoto, Ryota, Iwata, Nakao, Yoshikawa, Takeo, Ohmori, Tetsuro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Joule Inc. 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915240/
https://ncbi.nlm.nih.gov/pubmed/29688875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.170053
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