Circulating tumor DNA in early response assessment and monitoring of advanced colorectal cancer treated with a multi-kinase inhibitor

Predictive biomarkers are eagerly awaited in advanced colorectal cancer (aCRC). Targeted sequencing performed on tumor and baseline plasma samples in 20 patients with aCRC treated with regorafenib identified 89 tumor-specific mutations of which ≥50% are also present in baseline plasma. Droplet digit...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Vandeputte, Caroline, Kehagias, Pashalina, El Housni, Hakim, Ameye, Lieveke, Laes, Jean-François, Desmedt, Christine, Sotiriou, Christos, Deleporte, Amélie, Puleo, Francesco, Geboes, Karen, Delaunoit, Thierry, Demolin, Gauthier, Peeters, Marc, D’Hondt, Lionel, Janssens, Jos, Carrasco, Javier, Marechal, Raphaël, Galdon, Maria Gomez, Heimann, Pierre, Paesmans, Marianne, Flamen, Patrick, Hendlisz, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915153/
https://ncbi.nlm.nih.gov/pubmed/29707145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24879
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