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Prediction of tumor mutation burden in breast cancer based on the expression of ER, PR, HER-2, and Ki-67

OBJECTIVE: Cancer immunoediting is the process of eliminating highly immunogenic tumor cells by somatic evolution and protecting the host from tumor development in the host immune system. Frequencies of somatic mutations or tumor mutation burden (TMB) were associated with immunogenicity of breast ca...

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Pubblicato in:Onco Targets Ther
Autori principali: Xu, Junnan, Guo, Xiangyu, Jing, Mingxi, Sun, Tao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914885/
https://ncbi.nlm.nih.gov/pubmed/29719409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S159830
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