Dual-targeting biomimetic delivery for anti-glioma activity via remodeling the tumor microenvironment and directing macrophage-mediated immunotherapy

Tumor-associated macrophages (TAMs) are the major components in the tumor microenvironment (TME). The polarization from the protumor M2 (TAM2) to antitumor M1 (TAM1) phenotype can not only lift the immunosuppressive constraints and elicit cytotoxic T-cell immunity but also augment the chemotherapy e...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Zhao, Pengfei, Wang, Yonghui, Kang, Xuejia, Wu, Aihua, Yin, Weimin, Tang, Yisi, Wang, Jinyu, Zhang, Meng, Duan, Yifei, Huang, Yongzhuo
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914428/
https://ncbi.nlm.nih.gov/pubmed/29732051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04853j
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