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Oxidative Stress Induces HSP90 Upregulation on the Surface of Primary Human Endothelial Cells: Role of the Antioxidant 7,8-Dihydroxy-4-methylcoumarin in Preventing HSP90 Exposure to the Immune System

We have previously demonstrated that human heat shock protein 90 (HSP90), an intracellular self protein, is the target of cellular and humoral autoimmune responses in patients with carotid atherosclerosis. In this study, we evaluated in vitro whether oxidative stress, a feature of atherosclerotic pl...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Profumo, Elisabetta, Buttari, Brigitta, Tinaburri, Lavinia, D'Arcangelo, Daniela, Sorice, Maurizio, Capozzi, Antonella, Garofalo, Tina, Facchiano, Antonio, Businaro, Rita, Kumar, Prashant, Singh, Brajendra K., Parmar, Virinder S., Saso, Luciano, Riganò, Rachele
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914108/
https://ncbi.nlm.nih.gov/pubmed/29849874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2373167
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