A Novel Inhibitor of the LolCDE ABC Transporter Essential for Lipoprotein Trafficking in Gram-Negative Bacteria

The outer membrane is an essential structural component of Gram-negative bacteria that is composed of lipoproteins, lipopolysaccharides, phospholipids, and integral β-barrel membrane proteins. A dedicated machinery, called the Lol system, ensures proper trafficking of lipoproteins from the inner to...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Nickerson, Nicholas N., Jao, Christine C., Xu, Yiming, Quinn, John, Skippington, Elizabeth, Alexander, Mary Kate, Miu, Anh, Skelton, Nicholas, Hankins, Jessica V., Lopez, Michael S., Koth, Christopher M., Rutherford, Steven, Nishiyama, Mireille
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2018
Ämnen:
Experimental Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913989/
https://ncbi.nlm.nih.gov/pubmed/29339384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02151-17
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