Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity

Malaria remains a global health burden partly due to Plasmodium parasite resistance to first-line therapeutics. The molecular chaperone heat shock protein 90 (Hsp90) has emerged as an essential protein for blood-stage Plasmodium parasites, but details about its function during malaria's elusive...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Posfai, Dora, Eubanks, Amber L., Keim, Allison I., Lu, Kuan-Yi, Wang, Grace Z., Hughes, Philip F., Kato, Nobutaka, Haystead, Timothy A., Derbyshire, Emily R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913967/
https://ncbi.nlm.nih.gov/pubmed/29339390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01799-17
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