Coxiella burnetii Subverts p62/Sequestosome 1 and Activates Nrf2 Signaling in Human Macrophages

Coxiella burnetii is the causative agent of human Q fever, a debilitating flu-like illness that can progress to chronic disease presenting as endocarditis. Following inhalation, C. burnetii is phagocytosed by alveolar macrophages and generates a lysosome-like replication compartment termed the paras...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Winchell, Caylin G., Dragan, Amanda L., Brann, Katelynn R., Onyilagha, Frances I., Kurten, Richard C., Voth, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913852/
https://ncbi.nlm.nih.gov/pubmed/29483292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00608-17
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