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Type IV Pili Promote Clostridium difficile Adherence and Persistence in a Mouse Model of Infection

Cyclic diguanylate (c-di-GMP) is a second messenger that regulates the transition from motile to sessile lifestyles in numerous bacteria and controls virulence factor production in a variety of pathogens. In Clostridium difficile, c-di-GMP negatively regulates flagellum biosynthesis and swimming mot...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: McKee, Robert W., Aleksanyan, Naira, Garrett, Elizabeth M., Tamayo, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913833/
https://ncbi.nlm.nih.gov/pubmed/29483294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00943-17
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