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Complex II phosphorylation is triggered by unbalanced redox homeostasis in cells lacking complex III

A marked stimulation of complex II enzymatic activity was detected in cybrids bearing a homoplasmic MTCYB microdeletion causing disruption of both the activity and the assembly of complex III, but not in cybrids harbouring another MTCYB mutation affecting only the complex III activity. Moreover, com...

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Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Tropeano, Concetta Valentina, Fiori, Jessica, Carelli, Valerio, Caporali, Leonardo, Daldal, Fevzi, Ghelli, Anna Maria, Rugolo, Michela
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913658/
https://ncbi.nlm.nih.gov/pubmed/29269267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2017.12.003
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