Clinical significance of CD73 in triple-negative breast cancer: multiplex analysis of a phase III clinical trial

BACKGROUND: CD73 is an ecto-enzyme that promotes tumor immune escape through the production of immunosuppressive extracellular adenosine in the tumor microenvironment. Several CD73 inhibitors and adenosine receptor antagonists are being evaluated in phase I clinical trials. PATIENTS AND METHODS: Ful...

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Vydáno v:Ann Oncol
Hlavní autoři: Buisseret, L, Pommey, S, Allard, B, Garaud, S, Bergeron, M, Cousineau, I, Ameye, L, Bareche, Y, Paesmans, M, Crown, J P A, Di Leo, A, Loi, S, Piccart-Gebhart, M, Willard-Gallo, K, Sotiriou, C, Stagg, J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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Original articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913595/
https://ncbi.nlm.nih.gov/pubmed/29145561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdx730
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