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Bumetanide blocks the acquisition of conditioned fear in adult rats
BACKGROUND AND PURPOSE: Bumetanide has anxiolytic effects in rat models of conditioned fear. As a loop diuretic, bumetanide blocks cation–chloride co‐transport and this property may allow bumetanide to act as an anxiolytic by modulating GABAergic synaptic transmission in the CNS. Its potential for t...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5913399/ https://ncbi.nlm.nih.gov/pubmed/29235092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14125 |
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