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Anisomycin prevents OGD-induced necroptosis by regulating the E3 ligase CHIP

Necroptosis is an essential pathophysiological process in cerebral ischemia-related diseases. Therefore, targeting necroptosis may prevent cell death and provide a much-needed therapy. Ansiomycin is an inhibitor of protein synthesis which can also activate c-Jun N-terminal kinases. The present study...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tang, Mi-bo, Li, Yu-sheng, Li, Shao-hua, Cheng, Yuan, Zhang, Shuo, Luo, Hai-yang, Mao, Cheng-yuan, Hu, Zheng-wei, Schisler, Jonathan C., Shi, Chang-he, Xu, Yu-ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913227/
https://ncbi.nlm.nih.gov/pubmed/29686306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24414-y
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