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Neurochemical abnormalities in premanifest and early spinocerebellar ataxias

OBJECTIVE: To investigate whether early neurochemical abnormalities are detectable by high field magnetic resonance spectroscopy (MRS) in individuals with spinocerebellar ataxias (SCAs) 1, 2, 3 and 6, including patients without manifestation of ataxia. METHODS: A cohort of 100 subjects (N=18–21 in e...

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Bibliografische gegevens
Gepubliceerd in:Ann Neurol
Hoofdauteurs: Joers, James M., Deelchand, Dinesh K., Lyu, Tianmeng, Emir, Uzay E., Hutter, Diane, Gomez, Christopher M., Bushara, Khalaf O., Eberly, Lynn E., Öz, Gülin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912959/
https://ncbi.nlm.nih.gov/pubmed/29575033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25212
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