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A zebrafish and mouse model for selective pruritus via direct activation of TRPA1
Little is known about the capacity of lower vertebrates to experience itch. A screen of itch-inducing compounds (pruritogens) in zebrafish larvae yielded a single pruritogen, the TLR7 agonist imiquimod, that elicited a somatosensory neuron response. Imiquimod induced itch-like behaviors in zebrafish...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912907/ https://ncbi.nlm.nih.gov/pubmed/29561265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32036 |
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