CD44-mediated hyaluronan binding marks proliferating hematopoietic progenitor cells and promotes bone marrow engraftment

CD44 is a widely expressed cell adhesion molecule that binds to the extracellular matrix component, hyaluronan. However, this interaction is not constitutive in most immune cells at steady state, as the ability of CD44 to engage hyaluronan is highly regulated. While activated T cells and macrophages...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee-Sayer, Sally S. M., Dougan, Meghan N., Cooper, Jesse, Sanderson, Leslie, Dosanjh, Manisha, Maxwell, Christopher A., Johnson, Pauline
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912764/
https://ncbi.nlm.nih.gov/pubmed/29684048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196011
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