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Potential mechanisms for low uric acid in Parkinson disease

Several epidemiologic studies have described an association between low serum uric acid (UA) and Parkinson disease (PD). Uric acid is a known antioxidant, and one proposed mechanism of neurodegeneration in PD is oxidative damage of dopamine neurons. However, other complex metabolic pathways may cont...

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Detalhes bibliográficos
Publicado no:J Neural Transm (Vienna)
Main Authors: Sampat, Radhika, Young, Sarah, Rosen, Ami, Bernhard, Douglas, Millington, David, Factor, Stewart, Jinnah, H. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912672/
https://ncbi.nlm.nih.gov/pubmed/26747026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-015-1503-4
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