Polyarginine Interacts More Strongly and Cooperatively than Polylysine with Phospholipid Bilayers

The interactions of two highly positively charged short peptide sequences with negatively charged lipid bilayers were explored by fluorescence binding assays and all-atom molecular dynamics simulations. The bilayers consisted of mixtures of phosphatidylglycerol (PG) and phosphatidylcholine (PC) lipi...

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Udgivet i:J Phys Chem B
Main Authors: Robison, Aaron D., Sun, Simou, Poyton, Matthew F., Johnson, Gregory A., Pellois, Jean-Philippe, Jungwirth, Pavel, Vazdar, Mario, Cremer, Paul S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912336/
https://ncbi.nlm.nih.gov/pubmed/27571288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b05604
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