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Essential Metal Uptake in Gram-negative Bacteria: X-ray Fluorescence, Radioisotopes, and Cell Fractionation

We demonstrate a scalable method for the separation of the bacterial periplasm from the cytoplasm. This method is used to purify periplasmic protein for the purpose of biophysical characterization, and measure substrate transfer between periplasmic and cytoplasmic compartments. By carefully limiting...

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Detalles Bibliográficos
Publicado en:J Vis Exp
Main Authors: Radka, Christopher D., Radford, Lauren L., Massicano, Adriana V.F., DeLucas, Lawrence J., Lapi, Suzanne E., Aller, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado: MyJove Corporation 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912328/
https://ncbi.nlm.nih.gov/pubmed/29443084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57169
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