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Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage
DNA damage induces specific signaling and repair responses in the cell, which is critical for protection of genome integrity. Laser microirradiation became a valuable experimental tool to investigate the DNA damage response (DDR) in vivo. It allows real-time high-resolution single-cell analysis of m...
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| Published in: | J Vis Exp |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MyJove Corporation
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912314/ https://ncbi.nlm.nih.gov/pubmed/29443023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56213 |
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