Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage

DNA damage induces specific signaling and repair responses in the cell, which is critical for protection of genome integrity. Laser microirradiation became a valuable experimental tool to investigate the DNA damage response (DDR) in vivo. It allows real-time high-resolution single-cell analysis of m...

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書目詳細資料
發表在:J Vis Exp
Main Authors: Kong, Xiangduo, Cruz, Gladys M.S., Silva, Bárbara A., Wakida, Nicole M., Khatibzadeh, Nima, Berns, Michael W., Yokomori, Kyoko
格式: Artigo
語言:Inglês
出版: MyJove Corporation 2018
主題:
Genetics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912314/
https://ncbi.nlm.nih.gov/pubmed/29443023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56213
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