Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage

DNA damage induces specific signaling and repair responses in the cell, which is critical for protection of genome integrity. Laser microirradiation became a valuable experimental tool to investigate the DNA damage response (DDR) in vivo. It allows real-time high-resolution single-cell analysis of m...

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Bibliografski detalji
Izdano u:J Vis Exp
Glavni autori: Kong, Xiangduo, Cruz, Gladys M.S., Silva, Bárbara A., Wakida, Nicole M., Khatibzadeh, Nima, Berns, Michael W., Yokomori, Kyoko
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2018
Teme:
Genetics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912314/
https://ncbi.nlm.nih.gov/pubmed/29443023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56213
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