Direct and cytokine‐mediated effects of albumin‐fused growth hormone, TV‐1106, on CYP enzyme expression in human hepatocytes in vitro

Some biologics can modulate cytokines that may lead to changes in expression of drug‐metabolizing enzymes and cause drug‐drug interactions (DDI). DDI potential of TV‐1106—an albumin‐fused growth hormone (GH)—was investigated. In this study, human blood was exposed to recombinant human growth hormone...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmacol Res Perspect
Prif Awduron: Czerwiński, Maciej, Amunom, Immaculate, Piryatinsky, Victor, Hallak, Hussein, Sahly, Yousif, Bar‐Ilan, Oren, Bolliger, Paul, Bassan, Merav
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911691/
https://ncbi.nlm.nih.gov/pubmed/29721322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.397
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