Implication of Interleukin-12/15/18 and Ruxolitinib in the Phenotype, Proliferation, and Polyfunctionality of Human Cytokine-Preactivated Natural Killer Cells

A brief in vitro stimulation of natural killer (NK) cells with interleukin (IL)-12, IL-15, and IL-18 endow them a memory-like behavior, characterized by higher effector responses when they are restimulated after a resting period of time. These preactivated NK cells, also known as cytokine-induced me...

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Опубликовано в: :Front Immunol
Главные авторы: Terrén, Iñigo, Mikelez, Idoia, Odriozola, Irati, Gredilla, Andrea, González, Javier, Orrantia, Ane, Vitallé, Joana, Zenarruzabeitia, Olatz, Borrego, Francisco
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911648/
https://ncbi.nlm.nih.gov/pubmed/29713323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00737
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