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Inhibition of PC4 radiosensitizes non‐small cell lung cancer by transcriptionally suppressing XLF

Positive cofactor 4 (PC4) participates in DNA damage repair and involved in nonhomologous end joining (NHEJ). Our previous results demonstrated that knockdown of PC4 downregulated the expression of XRCC4‐like factor (XLF) in esophageal squamous cell carcinoma. However, the mechanism how PC4 regulate...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Zhang, Tian, Liu, Xiaojie, Chen, Xiuli, Wang, Jing, Wang, Yuwen, Qian, Dong, Pang, Qingsong, Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911594/
https://ncbi.nlm.nih.gov/pubmed/29522271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1332
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