PARP inhibitor olaparib sensitizes cholangiocarcinoma cells to radiation

Cholangiocarcinoma (CCA) is a highly malignant tumor with resistance to radiotherapy alone. Olaparib, a highly potent poly(ADP‐ribose) polymerase (PARP) inhibitor, has been shown to sensitize many types of tumor to radiotherapy. However, the effect of olaparib, either as monotherapy or as combinatio...

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Bibliografiske detaljer
Udgivet i:Cancer Med
Main Authors: Mao, Yize, Huang, Xin, Shuang, Zeyu, Lin, Guohe, Wang, Jun, Duan, Fangting, Chen, Jianlin, Li, Shengping
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Cancer Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911590/
https://ncbi.nlm.nih.gov/pubmed/29479816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1318
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