microRNA-219 Reduces Viral Load and Pathologic Changes in Theiler's Virus-Induced Demyelinating Disease

Analysis of microRNA (miR) expression in the central nervous system white matter of SJL mice infected with the BeAn strain of Theiler’s murine encephalomyelitis virus (TMEV) revealed a significant reduction of miR-219, a critical regulator of myelin assembly and repair. Restoration of miR-219 expres...

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Publicado no:Mol Ther
Main Authors: Moyano, Ana Lis, Steplowski, Jeffrey, Wang, Haibo, Son, Kyung-No, Rapolti, Diana I., Marshall, Jeffrey, Elackattu, Vince, Marshall, Michael S., Hebert, Amy K., Reiter, Cory R., Ulloa, Viviana, Pituch, Katarzyna C., Givogri, Maria I., Lu, Q. Richard, Lipton, Howard L., Bongarzone, Ernesto R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910888/
https://ncbi.nlm.nih.gov/pubmed/29433936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.01.008
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