Characterizing the human hippocampus in aging and Alzheimer’s disease using a computational atlas derived from ex vivo MRI and histology

Although the hippocampus is one of the most studied structures in the human brain, limited quantitative data exist on its 3D organization, anatomical variability, and effects of disease on its subregions. Histological studies provide restricted reference information due to their 2D nature. In this p...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Adler, Daniel H., Wisse, Laura E. M., Ittyerah, Ranjit, Pluta, John B., Ding, Song-Lin, Xie, Long, Wang, Jiancong, Kadivar, Salmon, Robinson, John L., Schuck, Theresa, Trojanowski, John Q., Grossman, Murray, Detre, John A., Elliott, Mark A., Toledo, Jon B., Liu, Weixia, Pickup, Stephen, Miller, Michael I., Das, Sandhitsu R., Wolk, David A., Yushkevich, Paul A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910869/
https://ncbi.nlm.nih.gov/pubmed/29592955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801093115
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