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Identification of long-lived synaptic proteins by proteomic analysis of synaptosome protein turnover

Memory formation is believed to result from changes in synapse strength and structure. While memories may persist for the lifetime of an organism, the proteins and lipids that make up synapses undergo constant turnover with lifetimes from minutes to days. The molecular basis for memory maintenance m...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Heo, Seok, Diering, Graham H., Na, Chan Hyun, Nirujogi, Raja Sekhar, Bachman, Julia L., Pandey, Akhilesh, Huganir, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910858/
https://ncbi.nlm.nih.gov/pubmed/29610302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720956115
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