Stability of an ophthalmic formulation of polyhexamethylene biguanide in gamma-sterilized and ethylene oxide sterilized low density polyethylene multidose eyedroppers

BACKGROUND: Polyhexamethylene biguanide (PHMB) eye drops are a frequently used medication to treat Acanthamoeba keratitis. In the absence of marketed PHMB eye drops, pharmacy-compounding units are needed to prepare this much needed treatment, but the lack of validated PHMB stability data severely li...

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Vydáno v:PeerJ
Hlavní autoři: Bouattour, Yassine, Chennell, Philip, Wasiak, Mathieu, Jouannet, Mireille, Sautou, Valérie
Médium: Artigo
Jazyk:Inglês
Vydáno: PeerJ Inc. 2018
Témata:
Drugs and Devices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910790/
https://ncbi.nlm.nih.gov/pubmed/29682408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4549
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