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Comparison of normalization methods for the analysis of metagenomic gene abundance data

BACKGROUND: In shotgun metagenomics, microbial communities are studied through direct sequencing of DNA without any prior cultivation. By comparing gene abundances estimated from the generated sequencing reads, functional differences between the communities can be identified. However, gene abundance...

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Publicat a:BMC Genomics
Autors principals: Pereira, Mariana Buongermino, Wallroth, Mikael, Jonsson, Viktor, Kristiansson, Erik
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910605/
https://ncbi.nlm.nih.gov/pubmed/29678163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4637-6
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