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Expression of ATF6 as a marker of pre-cancerous atypical change in ulcerative colitis-associated colorectal cancer: a potential role in the management of dysplasia

BACKGROUND: Diagnosis of low-grade dysplasia (LGD) is important in the management of ulcerative colitis (UC), but it is often difficult to distinguish LGD from inflammatory regenerative epithelium. The unfolded protein response (UPR) is activated in inflammatory bowel disease and malignancies. We ai...

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Detalhes bibliográficos
Publicado no:J Gastroenterol
Main Authors: Hanaoka, Marie, Ishikawa, Toshiaki, Ishiguro, Megumi, Tokura, Michiyo, Yamauchi, Shinichi, Kikuchi, Akifumi, Uetake, Hiroyuki, Yasuno, Masamichi, Kawano, Tatsuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910497/
https://ncbi.nlm.nih.gov/pubmed/28884228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00535-017-1387-1
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