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Downregulation of p53 drives autophagy during human trophoblast differentiation

The placental barrier is crucial for the supply of nutrients and oxygen to the developing fetus and is maintained by differentiation and fusion of mononucleated cytotrophoblasts into the syncytiotrophoblast, a process only partially understood. Here transcriptome and pathway analyses during differen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Mol Life Sci
Hauptverfasser: Gauster, Martin, Maninger, Sabine, Siwetz, Monika, Deutsch, Alexander, El-Heliebi, Amin, Kolb-Lenz, Dagmar, Hiden, Ursula, Desoye, Gernot, Herse, Florian, Prokesch, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910494/
https://ncbi.nlm.nih.gov/pubmed/29080089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-017-2695-6
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