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HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency

Most studies of HIV latency focus on the peripheral population of resting memory T cells, but the brain also contains a distinct reservoir of HIV-infected cells in microglia, perivascular macrophages, and astrocytes. Studying HIV in the brain has been challenging, since live cells are difficult to r...

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Detalhes bibliográficos
Publicado no:J Neurovirol
Main Authors: Llewellyn, George N., Alvarez-Carbonell, David, Chateau, Morgan, Karn, Jonathan, Cannon, Paula M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910454/
https://ncbi.nlm.nih.gov/pubmed/29256041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-017-0604-2
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