aPKCζ-dependent Repression of Yap is Necessary for Functional Restoration of Irradiated Salivary Glands with IGF-1

Xerostomia and salivary hypofunction often result as a consequence of radiation therapy for head and neck cancers, which are diagnosed in roughly 60,000 individuals every year in the U.S. Due to the lack of effective treatments for radiation-induced salivary hypofunction, stem cell-based therapies h...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chibly, Alejandro M., Wong, Wen Yu, Pier, Maricela, Cheng, Hongqiang, Mu, Yongxin, Chen, Ju, Ghosh, Sourav, Limesand, Kirsten H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910385/
https://ncbi.nlm.nih.gov/pubmed/29679075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24678-4
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