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Heparin-Fibronectin Interactions in the Development of Extracellular Matrix Insolubility

During extracellular matrix (ECM) assembly, fibronectin (FN) fibrils are irreversibly converted into a detergent-insoluble form which, through FN’s multi-domain structure, can interact with collagens, matricellular proteins, and growth factors to build a definitive matrix. FN also has heparin/hepara...

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Detalhes bibliográficos
Publicado no:Matrix Biol
Main Authors: Raitman, Irene, Huang, Mia L., Williams, Selwyn A., Friedman, Benjamin, Godula, Kamil, Schwarzbauer, Jean E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910196/
https://ncbi.nlm.nih.gov/pubmed/29223498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2017.11.012
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