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Synthetic Access to the Mandelalide Family of Macrolides: Development of an Anion Relay Chemistry Strategy

The mandelalides comprise a family of structurally complex marine macrolides that display significant cytotoxicity against several human cancer cell lines. Presented here is a full account on the development of an Anion Relay Chemistry (ARC) strategy for the total synthesis of (−)-mandelalides A and...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Nguyen, Minh H., Imanishi, Masashi, Kurogi, Taichi, Wan, Xuemei, Ishmael, Jane E., McPhail, Kerry L., Smith, Amos B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910188/
https://ncbi.nlm.nih.gov/pubmed/29480727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.8b00268
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