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Proliferative and metastatic roles for Phospholipase D in mouse models of cancer

Phospholipase D (PLD) activity has been proposed to facilitate multiple steps in cancer progression including growth, metabolism, angiogenesis, and mobility. The canonical enzymes PLD1 and PLD2 enact their diverse effects through hydrolyzing the membrane lipid phosphatidylcholine to generate the sec...

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Detalhes bibliográficos
Publicado no:Adv Biol Regul
Main Authors: Roth, Eric, Frohman, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910061/
https://ncbi.nlm.nih.gov/pubmed/29154090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2017.11.004
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