Population pharmacokinetics and dosing optimization of cefathiamidine in children with hematologic infection

PURPOSE: Cefathiamidine, a first-generation cephalosporin, has approval from the China Food and Drug Administration for the treatment of infections caused by susceptible bacteria in both adults and children. As pharmacokinetic data are limited in the pediatric population, we aimed to evaluate the po...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Zhi, Li-Juan, Wang, Li, Chen, Xing-Kai, Zhai, Xiao-Ying, Wen, Li, Dong, Lei, Jacqz-Aigrain, Evelyne, Shi, Zhong-Ren, Zhao, Wei
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909787/
https://ncbi.nlm.nih.gov/pubmed/29713143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S160329
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