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Neuroinflammation in Alzheimer's Disease

Increasing evidence suggests that Alzheimer's disease pathogenesis is not restricted to the neuronal compartment but strongly interacts with immunological mechanisms in the brain. Misfolded and aggregated proteins bind to pattern recognition receptors on micro- and astroglia and trigger an inna...

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Detalhes bibliográficos
Publicado no:Lancet Neurol
Main Authors: Heneka, Michael T., Carson, Monica J., El Khoury, Joseph, Landreth, Gary E., Brosseron, Frederik, Feinstein, Douglas L., Jacobs, Andreas H., Wyss-Coray, Tony, Vitorica, Javier, Ransohoff, Richard M., Herrup, Karl, Frautschy, Sally A., Finsen, Bente, Brown, Guy C., Verkhratsky, Alexei, Yamanaka, Koji, Koistinaho, Jari, Latz, Eicke, Halle, Annett, Petzold, Gabor C., Town, Terrence, Morgan, Dave, Shinohara, Mari L., Perry, V. Hugh, Holmes, Clive, Bazan, Nicolas G., Brooks, David J., Hunot, Stephane, Joseph, Bertrand, Deigendesch, Nikolaus, Garaschuk, Olga, Boddeke, Erik, Dinarello, Charles A., Breitner, John C., Cole, Greg M., Golenbock, Douglas T., Kummer, Markus P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909703/
https://ncbi.nlm.nih.gov/pubmed/25792098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(15)70016-5
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