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Phospholipase D in T cell receptor-mediated signaling and T cell activation

Phospholipase D is an enzyme that catalyzes the hydrolysis of phosphatidylcholine, the major phospholipid in the plasma membrane, to generate an important signaling lipid, phosphatidic acid (PA). PA is a second messenger that regulates vesicular trafficking, cytoskeletal reorganization, cell signali...

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Bibliographic Details
Published in:J Immunol
Main Authors: Zhu, Minghua, Foreman, Daniel, O'Brien, Sarah A., Jin, Yuefei, Zhang, Weiguo
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909698/
https://ncbi.nlm.nih.gov/pubmed/29386256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701291
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