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Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized care

Drug-resistant TB (DR-TB) remains a significant challenge in TB treatment and control programmes worldwide. Advances in sequencing technology have significantly increased our understanding of the mechanisms of resistance to anti-TB drugs. This review provides an update on advances in our understandi...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Dookie, Navisha, Rambaran, Santhuri, Padayatchi, Nesri, Mahomed, Sharana, Naidoo, Kogieleum
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909630/
https://ncbi.nlm.nih.gov/pubmed/29360989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx506
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