Upregulation of Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Mediates the Reversal Effect of Verapamil on Chemo-Resistance to Adriamycin of Hepatocellular Carcinoma

BACKGROUND: The aim of this study was to investigate the role of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) in the reversal effect of verapamil (VER) on chemo-resistance to Adriamycin (ADM) in treatment of hepatocellular carcinoma (HCC). MATERIAL/METHODS: HCC cell lines SMMC-7721 and BEL-7402...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Yang, Guangshan, Fan, Gaofei, Zhang, Tengyue, Ma, Kelong, Huang, Jin, Liu, Miao, Teng, Xiaolu, Xu, Kun, Fan, Pingsheng, Cheng, Dongmiao
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2018
Assuntos:
Lab/In Vitro Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909418/
https://ncbi.nlm.nih.gov/pubmed/29627846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.908925
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