Dose Dependencies and Biocompatibility of Renal Clearable Gold Nanoparticles: From Mice to Non-human Primates

While dose dependencies in pharmacokinetics and clearance are often observed in clinically used small molecules, very few studies have been dedicated to the understandings of potential dose-dependent in vivo transport of nanomedicines. Here we report that the pharmacokinetics and clearance of renal...

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Veröffentlicht in:Angew Chem Int Ed Engl
Hauptverfasser: Xu, Jing, Yu, Mengxiao, Peng, Chuanqi, Carter, Phoebe, Tian, Jia, Ning, Xuhui, Zhou, Qinhan, Tu, Qiu, Zhang, Greg, Dao, Anthony, Jiang, Xingya, Kapur, Payal, Hsieh, Jer-Tsong, Zhao, Xudong, Liu, Pengyu, Zheng, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909189/
https://ncbi.nlm.nih.gov/pubmed/29160029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201710584
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