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Thiodigalactoside–Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors

[Image: see text] Galectin inhibitors are urgently needed to understand the mode of action and druggability of different galectins, but potent and selective agents still evade researchers. Small-sized inhibitors based on thiodigalactoside (TDG) have shown their potential while modifications at their...

詳細記述

保存先:
書誌詳細
出版年:Bioconjug Chem
主要な著者: Zhang, Hao, Laaf, Dominic, Elling, Lothar, Pieters, Roland J.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2018
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909177/
https://ncbi.nlm.nih.gov/pubmed/29474087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00047
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