Depletion of Airway Submucosal Glands and TP63(+)KRT5(+) Basal Cells in Obliterative Bronchiolitis

Rationale: Obliterative bronchiolitis (OB) is a major cause of mortality after lung transplantation. Depletion of airway stem cells (SCs) may lead to fibrosis in OB. Objectives: Two major SC compartments in airways are submucosal glands (SMGs) and surface airway p63 (also known as TP63 [tumor protei...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Swatek, Anthony M., Lynch, Thomas J., Crooke, Adrianne K., Anderson, Preston J., Tyler, Scott R., Brooks, Leonard, Ivanovic, Marina, Klesney-Tait, Julia A., Eberlein, Michael, Pena, Tahuanty, Meyerholz, David K., Engelhardt, John F., Parekh, Kalpaj R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909161/
https://ncbi.nlm.nih.gov/pubmed/29236513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201707-1368OC
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