Association of STAT-3 rs1053004 and VDR rs11574077 With FOLFIRI-Related Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients

Pharmacogenomics has largely been applied to the personalization of irinotecan-based treatment, focusing mainly on the study of genetic variants in adsorption, distribution, metabolism, and excretion (ADME) genes. The transcriptional control of ADME gene expression is mediated by a set of nuclear fa...

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Vydáno v:Front Pharmacol
Hlavní autoři: De Mattia, Elena, Cecchin, Erika, Montico, Marcella, Labriet, Adrien, Guillemette, Chantal, Dreussi, Eva, Roncato, Rossana, Bignucolo, Alessia, Buonadonna, Angela, D’Andrea, Mario, Coppola, Luigi, Lonardi, Sara, Lévesque, Eric, Jonker, Derek, Couture, Félix, Toffoli, Giuseppe
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908896/
https://ncbi.nlm.nih.gov/pubmed/29706892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00367
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